Cetilistat Powder Cas 282526-98-1 Weight Loss API Material

Weight Loss Raw Materials The Cetilistat is an organic compound with the formula C25H39NO3. The IUPAC name of this chemical is 2-hexadecoxy-6-methyl-3,1-benzoxazin-4-one. With the CAS registry number 282526-98-1, it is also named as 4H-3,1-benzoxazin-4-one, 2-(hexadecyloxy)-6-methyl-. Weight Management Materials The product's classification code is Treatment of obesity. Besides, it is a drug designed to treat obesity. It acts in the same way as the older drug orlistat by inhibiting pancreatic lipase, an enzyme that breaks down triglycerides in the intestine. Without this enzyme, triglycerides from the diet are prevented from being hydrolyzed into absorbable free fatty acids and are excreted undigested. 

Cetilistat Powder Cas 282526-98-1 Weight Loss API Material 

[Product Name]: Cetilistat 
[Apperance]: White Powder

[Specification]: 99%

[Test Method]: HPLC
[Storage]: Store in a cool, dry place and sealed container.

Losing Weight Materials Cetilistat is a drug designed to treat obesity. It acts in the same way as the older drug orlistat(Xenical) by inhibiting pancreatic lipase, an enzyme that breaks down triglycerides in the intestine. Without this enzyme, triglycerides from the diet are prevented from being hydrolyzed into absorbable free fatty acids and are excreted undigested.
In human trials, cetilistat was shown to produce similar weight loss to orlistat, but also produced similar side effects such as oily, loose stools, fecal incontinence, frequent bowel movements, andflatulence.It is likely that the same precautions would apply in that absorption of fat-soluble vitamins and other fat-soluble nutrients may be inhibited, requiring vitamin supplements to be used to avoid deficiencies.
Cetilistat has completed Phase 1 and 2 trials in the West and is currently in Phase 3 trials in Japan where it is partnered with Takeda. Norgina BV has now acquired the full global rights to cetilistat from Alizyme after the latter went into administration.
A published phase 2 trial found cetilistat significantly reduced weight with and was better tolerated than orlistat.

In human trials, cetilistat was shown to produce similar weight loss to orlistat, but also produced similar side effects such as oily, loose stools, fecal incontinence, frequent bowel movements, andflatulence.It is likely that the same precautions would apply in that absorption of fat-soluble vitamins and other fat-soluble nutrients may be inhibited, requiring vitamin supplements to be used to avoid deficiencies.

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