Pharmaceutical Intermediates Ingredients Probenecid is a medication that increases uric acid excretion in the urine. It is primarily used in treating gout and hyperuricemia.Probenecid was developed as an alternative to caronamide to competitively inhibit renal excretion of some drugs, thereby increasing their plasma concentration and prolonging their effects. This Medicine Raw Material is mainly used as Medical Intermediate Ingredients,Ease Pain Ingredients,Anti-Rheumatism Ingredients,Ease Joint Pain Ingredients.
[Product Name]: Probenecid
[Appearance]: White powder
[Specification]: 99%
[Test Method]: HPLC
[Cas No.]: 57-66-9
[M.F.]:C13H19NO4S
[M.W.]:285.36
[Solubility]: Soluble in acetone, and slightly soluble in ethanol or chloroform, but almost insoluble in water. It is also soluble in dilute sodium hydroxide solution, but almost insoluble in dilute acid.
Medical uses
1. Probenecid is primarily used to treat gout and hyperuricemia;
2. Probenecid is sometimes used to increase the concentration of some antibiotics. Specifically a small amount of evidence supports the use of intravenous cefazolin once rather than three times a day when it is combined with probenecid;
3. It has also found use as a masking agent, potentially helping athletes using performance-enhancing substances to avoid detection by drug tests.
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