Anti-Microbia And Anti-Inflammation Ingredients Gentamicin sulfate is a glycoside bactericidal antibiotic linked by amino sugar and ligand. Anti-Inflammation Ingredients It is the sulfate of gentamicin, and its antibacterial spectrum is similar to kanamycin. Mainly used for escherichia coli, dysentery bacillus, Klebsiella pneumoniae, Proteus, pseudomonas aeruginosa and other gram-negative bacteria caused by the system or local infection. Anti-Microbial Material Ophthalmology for conjunctivitis, keratitis, etc. Oral preparation for intestinal infections or colon surgery; It may also be used in combination with metronidazole or clindamycin to reduce the rate of infection during colon surgery. Gentamicin sulfate has good antibacterial effect on all kinds of gram-negative bacteria and gram-positive bacteria, and has good antibacterial effect on all kinds of enterobacteriaceae bacteria, such as Escherichia coli, Klebsiella, Proteus, Salmonella, Shigella, Enterobacter, Serratia and pseudomonas aeruginosa. Neisseria and Haemophilus influenzae are moderately sensitive to this product. Brucella, yersinia pestis, acinetobacter, fetal campylobacter also has a certain effect. About 80% of methicillin-sensitive strains in Staphylococcus (including Staphylococcus aureus and coagulase negative staphylococcus) had good antibacterial effect, but most of methicillin-resistant strains were resistant to gentamicin sulfate. The effect on streptococcus and streptococcus pneumoniae is poor, and enterococcus is mostly resistant to the drug. In recent years, gentamicin-resistant strains of Gram-negative bacilli have increased significantly. When used together with β lactam, synergistic antibacterial action can be obtained in most cases.
Gentamycin Sulfate Powder CAS 1405-41-0 AntiMicrobia
[Product Name]: Gentamycin sulfate
[Apperance]: White Crystalline Powder
[Specification]: 99%min
[Test Method]: HPLC
[Cas No.]: 1405-41-0
[M.F.]: C60H127N15O26S
[M.W.]: 1506.8
[Storage]: Store in a cool, dry place and sealed container.
1. Used for the treatment of sepsis, urinary tract infection, staphylococcal infection, endocarditis and other diseases
2. Clinically used for septicemia, respiratory tract infection, biliary tract infection, suppurative peritonitis, intracranial infection, urinary tract infection and dysentery caused by Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, dysentery bacillus, Klebsiella, Proteus and other sensitive bacteria.
2. Gentamicin blocks the transfer of peptidyl-TrNA (Peptidyl-TrNA) from the recipient site to the donor site by binding to the 30S ribosome subunit, causing a code misread. Gentamicin bactericidal effect on pseudomonas by binding to the outer membrane part of the cell membrane, replacing the original existing cation, so that the membrane is unstable, forming a cavity on the cell surface. Antimicrobial spectrum: Gram-negative bacteria, staphylococcus and other gram-positive bacteria.
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