Herbal Extracts Camptothecin is an alkaloid derived from the Chinese tree Camptotheca acuminata Decne. Herbal Extract Camptothecin and its derivatives are unique in their ability to inhibit DNA Topoisomerase I, by stabilizing a covalent reaction intermediate termed the cleavable complex which ultimately causes tumor cell death.The Natural Ingredients is widely believed that Herbal Extract Camptothecin analogs exhibited remarkable anti-tumour and anti-leukaemia activity. Topoisomerase is a basilic enzyme in the process of DNA replication, Herbs Extract Camptothecin is responsible for the winding / unwinding of the supercoiled DNA composing the chromosomes. If the chromosomes cannot be unwound, transcription of DNA message cannot occur and the protein cannot be synthesized, Herbal Extract Camptothecin ultimately causes cell death.At present, some Camptothecin analogs, either semi-synthetic or synthetic drug based on Camptothecin, have been applied cancerous therapy such as topotecan and irinotecan while others have been obtained satisfying curative effects in clinic. As Active Pharmaceutical Ingredients, it widely be used in Anti-Cancer Ingredients, Anti-Microbia And Anti-Inflammation Ingredients, Skin Treatment Ingredients, Liver Care Ingredients and Stomach Care Material .
[Product Name]: Amptotheca Acuminata Extract Camptothecin
[Latin Name]: Camptotheca acuminata Decne.[Appearance]: Yellow Crystal powder
[Specification]: 98%
[Test Method]: HPLC
[Cas No.]: 7689-03-4
[M.F.]: C20H16N2O4
[M.W.]: 348.35
[Solubility]:Soluble in ethanol, methyl alcohol, chloroform; unsoluble in the water.
1. Camptothecin can make changes in skin epidermal keratinization process;
2. Camptothecin is used for anti-cancer, anti-virus, immune inhibition, anti early pregnancy;
3. Camptothecin has the function of treatment of gastric cancer, liver cancer, head and neck cancer and leukemia.
1. Applied in health care products filed;
2. Applied in pharmaceutical filed;
3. Applied in cosmetics filed.
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