Treating Stomach--Proglumide Powder Active Pharmaceutical Ingredients

Active Pharmaceutical Ingredients Proglumide also called ProM, is an acid - resistant drug and treatment of peptic ulcer disease drugs.

Invigorating Stomach Material Proglumide can increase the content of hexosamine in gastric mucosa, promote the synthesis of glycoprotein, protect and promote the healing of gastric mucosa, improve the symptoms of peptic ulcer and promote the healing of ulcer. After treatment of peptic ulcer and gastritis, there was no rebound of gastric acid secretion. After treatment, gastric acid secretion remained at the normal level for half a year. In addition, proglamine also has a cholagogic effect, there are three ways:

① by stimulating bile acid independent bile secretion, is conducive to stone drainage and flushing, dredge biliary tract;

② By changing the stone-forming factors in bile, the concentration and displacement of bicarbonate increased obviously, while the concentration of free bilirubin, cholesterol and calcium ions decreased;

③ By antagonizing CCK and inhibiting endogenous CCK's promoting gallbladder contraction, the gallbladder capacity is expanded and bile components in the gallbladder are diluted, thus stone formation can be prevented. Proglumide is commonly used for gastric and twelvefinger ulcers, chronic superficial gastritis, duodenal globulitis.

Stomach Portect Material Proglumide has the effect of anti-gastrin, controlling gastric acid and inhibiting pepsin secretion. It can also protect and promote the healing of gastric mucosa. It can be used to treat gastric ulcer, duodenal ulcer, gastritis and other clinical symptoms of peptic ulcer improvement, ulcer healing has a good effect.

Use: for gastric and duodenal ulcer, gastritis (such as chronic superficial gastritis) and duodenal globulitis.